"Because amniotic membrane has anti-inflammatory and anti-fibrosis characteristics, it may reduce secondary scarring and help prevent recurrence of restrictive strabismus and the diplopia and pain that often accompany this type of strabismus," the authors said.
The retrospective, interventional case series included eight eyes of seven consecutive patients who had developed restrictive strabismus after periocular surgery due to conjunctival scarring, fat adherence syndrome or rectus muscle contracture.
After failed additional standard surgery to remove the adhesions, patients underwent amniotic membrane transplantation.
Six of seven patients experienced improved ocular motility, with no recurrent scarring. Their motility remained stable for the 5- to 13-month follow-up period, according to the study.
One patient had recurrent scarring with persistent diplopia.