"Use of a commercially available carboxymethylcellulose adhesion barrier at primary cesarean delivery did not reduce time to delivery, total operative time, or complications during repeat cesareans, according to findings of a retrospective cohort study published in the May issue of Obstetrics & Gynecology.
"Adhesions that occur as a result of a prior cesarean delivery have been implicated as one cause of delayed delivery of the neonate during repeat cesarean deliveries," write Rodney K. Edwards, MD, associate professor, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Alabama Birmingham School of Medicine, and colleagues. "Seprafilm (sodium hyaluronate and carboxymethylcellulose absorbable adhesion barrier) is a commercially available product that is indicated for use in patients undergoing abdominal or pelvic laparotomy as an adjunct that is intended to reduce the incidence, extent, and severity of adhesion formation between the abdominal wall and the intraabdominal viscera.... However, data regarding use of this product for adhesion prevention at the time of caesarean delivery are limited to a single study of 52 patients."
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