Efficacy of Tricyclic Antidepressant is Associated with Beta2-Adrenoceptor Genotype in Patients with Interstitial Cystitis

Efficacy of Tricyclic Antidepressant is Associated with Beta2-Adrenoceptor Genotype in Patients with Interstitial CystitisWednesday, 27 December 2006BERKELEY, CA (UroToday.com) - Tricyclic antidepressant therapy (amitriptyline in particular) is effective in treating the symptoms of PBS/IC. These drugs block the active transport system that is involved in the re-uptake of serotonin and noradrenaline.read more