Performing clinical studies involving hernia mesh devices: what every investigator should know about the FDA investigational device exemption (IDE) process.

Hernia. 2011 Sep 11. [Epub ahead of print]


Performing clinical studies involving hernia mesh devices: what every investigator should know about the FDA investigational device exemption (IDE) process.

Ashar BS, Dang JM, Krause D, Luke MC.

SourceOffice of Device Evaluation, Center for Devices and Radiological Health, US Food and Drug Administration, 10903 New Hampshire Avenue, WO 66, Room 422, Silver Spring, MD, 20850, USA, Binita.Ashar@fda.hhs.gov.



Abstract

The FDA's Center for Devices and Radiological Health (CDRH) is responsible for providing reasonable assurance of safety and effectiveness of all medical devices marketed within the US. To date, CDRH has cleared numerous hernia mesh devices for general use, but has not cleared/approved any mesh devices intended for certain specific uses, such as for infected wounds, hernia prevention, biofilm reduction, or prevention of adhesions. CDRH is requesting that manufacturers seeking specific hernia mesh device labeling claims consult with the Agency to determine the level of evidence necessary for justifying such claims.



PMID:21909977[PubMed - as supplied by publisher]
 
http://www.ncbi.nlm.nih.gov/pubmed/21909977